| Phospholipids coated microbubbles exposed to ultrasound (US) are known to deflate, with possible impact on the results of diagnostic imaging applications. This paper reports on an acousto-optic study of the behaviour of single microbubbles exposed to pulsed low-pressure excitation sequences over long time intervals, during which the bubbles experience ultrasound-induced deflation. The set-up provides radius and echo information that is combined to show resonance effects, and second harmonic responses as a function of diameter. |