Short Courses (10 in Total)
Overview of Short Courses (Please Click on the Links to Jump to the Courses):
8:00 A.M. - 12:00 Noon, Monday, October 11, 2010:
Short Course 1A (8:00 A.M. - 12:00 Noon, Monday, October 11, 2010):
Course Title: Photoacoustic Imaging and Sensing
Stanislav Emelianov , Biomedical Engineering Department, University of Texas at Austin, USA.
Course Description: This course is designed to provide both a broad overview and a comprehensive understanding of photoacoustic (also known as optoacoustic and, more generally, thermoacoustic) imaging, sensing, and spectroscopy. With a brief historical introduction, we will examine the foundations of photoacoustics, including derivations and a discussion of governing equations. We will also review relevant optical properties of the tissues and the related topics of laser-tissue interaction. The experimental aspects of photoacoustic imaging and sensing will then be discussed with emphasis on system hardware and signal/image processing algorithms. Techniques to increase contrast and to differentiate various tissues in photoacoustic imaging will be presented. The course will conclude with an overview of several experimental systems capable of photoacoustic imaging, as well as discussion of current and potential biomedical and clinical applications of photoacoustics.
Stanislav Emelianov received B.S. and M.S. degrees in Physics and Acoustics in 1986 and 1989, respectively, from the Moscow State University, and a Ph.D. degree in Physics in 1993 from the Moscow State University and the Institute of Mathematical Problems of Biology of the Russian Academy of Science. In 1989, he joined the Institute of Mathematical Problems of Biology, where he was engaged in both mathematical modeling of soft tissue biomechanics and experimental studies of noninvasive visualization of the mechanical properties of tissue. Following his graduate work, he moved to the University of Michigan, Ann Arbor, as a post-Doctoral Fellow in the Bioengineering Program and in the Electrical Engineering and Computer Science Department. From 1996 to 2002, Dr. Emelianov was a Research Scientist at the Biomedical Ultrasonics Laboratory of the Biomedical Engineering Department at the University of Michigan. During his tenure at Michigan, Dr. Emelianov was involved primarily in the theoretical and practical aspects of elasticity imaging using ultrasound and MRI. Dr. Emelianov is currently teaching and conducting research in the Department of Biomedical Engineering at the University of Texas at Austin. His research interests are in medical imaging and therapeutics, including ultrasound, photoacoustic, elasticity and multi-modality imaging, photothermal therapy, cellular/molecular imaging and therapy, functional imaging, etc.
Short Course 2A (8:00 A.M. - 12:00 Noon, Monday, October 11, 2010):
Course Title: Piezoelectric Ultrasound Transducer Fundamentals - Materials, Structure,
Behavior and Analysis
*Susan Trolier-McKinstry, **Sandy Cochran, ***Paul Reynolds and ****Christine Demore,*Materials Research Lab, Penn State University, PA, USA. **Institute for Medical Science and Technology, University of Dundee,UK. ***Weidlinger Associates Inc, Mountain View, CA, USA. ****Institute for Medical Science and Technology, University of Dundee,UK.
Course Description: Piezoelectric ultrasound transducers are a crucial component in mostultrasound systems, with applications including biomedical imaging and therapy, nondestructive
evaluation and underwater sonar. The content of this course covers topics providing a foundation of
understanding about the fundamentals of ultrasound transducers and an informed appreciation of
more advanced subjects in the state of the art. The course is divided into four sections.
Ceramic, single crystal and polymer piezoelectric materials are introduced in the first section,
along with mathematical descriptions for them and their behavior and an explanation of the
underlying physics. New materials such as ternary single crystals are compared with those in use
since the 1950s and topics of increasing interest including lead free materials are covered.
In the second section, the operating principles of transducers are described with particularly
reference to wave propagation. Electrical impedance spectroscopy is introduced as a key technique
for transducer characterisation, along with ultrasound transmission and reception techniques. The
different types of one-dimensional model are presented, and this leads to a description of external
electrical circuitry, including the latest integrated electronic implementations.
The third section covers waves, fields and signals. The field of a transducer is introduced through
the concept of its physical aperture, different wave modes, and reciprocity. Huygen’s principle is
outlined and techniques to predict ultrasonic field characteristics are presented. Advanced work on
shear waves in tissue is introduced. Electronic arrays are outlined and finite element analysis is used
to provide examples of transmitted fields. More advanced topics in long range transmission and thin
film devices are covered. The importance of signal analysis in the time and frequency domains is
emphasised, and this is illustrated with reference to time reversal techniques.
An example dual-element transducer design is used as a common thread to illustrate important
results throughout the course and practical demonstrations will be provided on materials
characterisation and analysis with electrical impedance spectroscopy, one-dimensional transducer
design software, and pulse-echo transducer operation.
Susan Trolier-McKinstry is a professor of ceramic science and engineering and director of the W.M. Keck Smart Materials Integration Laboratory at the Pennsylvania State University. Her mainresearch interests include dielectric and piezoelectric thin films, the development of texture in bulk
ceramic piezoelectrics, and spectroscopic ellipsometry. She obtained B.S., M.S., and Ph.D. degrees
in Ceramic Science at Penn State, and on graduation, joined the faculty there. She has held several
international visiting appointments and is a fellow or member of several learned societies. She is
past-president of Keramos and the Ceramics Education Council, and co-chairs the committee
revising the IEEE Standard on Ferroelectricity. She is currently junior past President of the IEEE
UFFC. She is the recipient of many awards and is particularly proud that 17 people she has
advised/co-advised hold faculty positions around the world.
Short Course 3A (8:00 A.M. - 12:00 Noon, Monday, October 11, 2010):
Course Title: Ultrasonic Signal PRocessing for Detection, Estimation and Compression
Jafar Saniie, Department of Electrical and Computer Engineering at Illinois Institute of Technology, Ramazan Demirli, Canfield Scientific, Inc., Fairfield, NJ and Erdal Oruklu, Department of Electrical and Computer Engineering at Illinois Institute of Technology
Course Description: In ultrasonic imaging systems, the patterns of detected echoes, often complex and non-stationary, correspond to the shape, size, and orientation of the reflectors and the scattering properties of the propagation path. Therefore, signal modeling and parameter estimation of the nonstationary ultrasonic echoes is critical for image analysis, target detection, object recognition, deconvolution and data compression. In this short course, we present (1) modeling and classification of reverberant echoes, (2) time-frequency analysis and chirplet echo estimations, (3) detection and deconvolution of ultrasonic backscattered echoes using expectation-maximization and matching pursuit methods, (4) statistical signal processing techniques based on split-spectrum processing for detecting flaw echoes masked by high grain scattering noise, (5) discrete wavelet transform for 3D data compression, and (6) system-on-chip realization of detection, estimation, and compression algorithms using reconfigurable FPGA devices. This course will cover several case studies such detecting defects in steam generator tubes used in nuclear power plants, transducer pulse-echo wavelet estimation, subsample time delay estimation, thickness sizing of thin layers, and flaw detection in large grained materials.
Jafar Saniie (IEEE Fellow for contributions to ultrasonic signal processing for detection, estimation and imaging) received his B.S. degree in Electrical Engineering from the University of Maryland in 1974. He received his M.S. degree in Biomedical Engineering in 1977 from Case Western Reserve University, Cleveland, OH, and his Ph.D. degree in Electrical Engineering in 1981 from Purdue University, West Lafayette, IN. In 1981 Dr. Saniie joined the Department of Applied Physics, University of Helsinki, Finland, to conduct research in photothermal and photoacoustic imaging. Since 1983 he has been with the Department of Electrical and Computer Engineering at Illinois Institute of Technology where he is the Filmer Professor, Director of the Embedded Computing and Signal Processing (ECASP) Research Laboratory, and Associate Chair and Director of Graduate Program. Dr. Saniie’s research interests and activities are in ultrasonic signal and image processing, statistical pattern recognition, estimation and detection, embedded digital systems, digital signal processing with field programmable gate arrays, and ultrasonic nondestructive testing and imaging. In particular, he has performed extensive work in the areas of frequency-diverse ultrasonic flaw enhancement techniques, ultrasonic data compression, ultrasonic imaging of reverberant multilayer structures, time-frequency analysis of ultrasonic signals, and applications of neural networks for detecting flaw echoes and classifying microstructural scattering. Dr. Saniie has been a Technical Program Committee member of the IEEE Ultrasonics Symposium since 1987 (currently he is the chair of Sensors, NDE and Industrial Applications), Associate Editor of the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control since 1994. He has over 200 publications and supervised 25 Ph.D. dissertations.
Short Course 4A (8:00 A.M. - 12:00 Noon, Monday, October 11, 2010):
Course Title: Microacoustic Devices as Chemical Sensors
Gerhard Fischerauer, University of Bayreuth, Germany.
Course Description: Microacoustic chemical sensors based, for instance, on quartz crystal microbalances (QCM) or surface acoustic wave (SAW) devices have been popular in laboratories around the world
for almost 30 years. They have also met with some commercial success, and one of the
underlying effects, viz., mass loading, is routinely used in thin-film technology to monitor film
growth during deposition. This shourt course aims at introducing the principles of such
sensors and typical issues likely to crop up during their application. The focus is on physical
and functional aspects with an emphasis on transduction mechanisms and terminal
characteristics. For this reason, the course might also appeal to those interested in microacoustic
sensors in general.
The course will be broken down into three sections. The first section covers the operating
priciples of microacoustic devices, their design and fabrication. Devices discussed include
QCMs and resonators, delay lines, and ID tags based on Rayleigh waves, Lamb waves,
Love waves, shear-horizontal waves, etc.
In the second section, possible interactions of the microacoustic waves with their environment
will be investigated. These interactions are of a primarily physical nature,
examples being mass loading, changes in electrical conductivity, and changes in elastic
properties. A chemical sensor is obtained by coating the devices with layers which selectively
incorporate the chemical species of interest. The details of the transduction process from
analyte concentration to acoustic wave properties to device terminal characteristics will be
described.
The final section is devoted to practical issues such as instrumentation (vector network
analyzer, oscillator, frequency counter, interrogation of RFID tags), suitable signal
characteristics, and disturbances of the measurement process. Typical non-idealities and
sources of misinterpretation of measured data are identified. Finally, we will discuss methods
to suppress the influence of temperature and to speed up the effective sensor response by
signal processing approaches.
Gerhard Fischerauer was born in Munich, Germany, in 1963. He received the Dipl.-Ing.and the Dr.-Ing. degrees from the Technical University of Munich, Germany, in 1989 and
1996, respectively. From 1990 to 1998 he was with the microacoustics group of Siemens
Corporate Technology, Munich, Germany, where he worked on low-loss SAW RF filters for
mobile communications, on SAW chemical sensors, and on SAW sensors for harsh
environments. In 1998, he joined Epcos (then Siemens Matsushita) as manager responsible
for the development of SAW IF and RF filters for third-generation mobile phone systems. He
then went on to head the department of SAW Basics and System Concepts, dealing with
such issues as novel filter technologies and optimization of physical device properties. In
2001, Dr. Fischerauer joined the University of Bayreuth, Germany, as full professor in charge
of the Chair of Metrology and Control Engineering. He has published more than 100
conference and journal articles in his areas of interest: SAW devices and other thin-film
sensors and microsystems; sensor signal conditioning, transmission, and processing; highfrequency
systems; electromagnetic compatibility; and general metrology.
Short Course 5A (8:00 A.M. - 12:00 Noon, Monday, October 11, 2010):
Course Title: Therapeutic Ultrasound
Lawrence A. Crum, Applied Physics Lab, Univ of Washington. Joo Ha Hwang, Dept of Medicine, Univ of Washington and Michael R. Bailey, Applied Physics Lab, Univ of Washington.
Course Description: The use of ultrasound in medicine is now quite commonplace and widespread, especially with therecent introduction of small, portable and relatively inexpensive, hand-held diagnostic imaging devices. Moreover, ultrasound has expanded beyond the imaging realm, with methods and
applications extending to novel therapeutic and surgical uses. These applications broadly include:
Tissue ablation, acoustocautery, body contouring, site-specific and ultrasound mediated drug
activity, extracorporeal lithotripsy, and the enhancement of natural physiological functions such as
wound healing and tissue regeneration. A particularly attractive aspect of this technology is that
diagnostic and therapeutic systems can be combined to produce totally non-invasive, imageguided
therapy. This general lecture will review a number of these exciting new applications of
ultrasound and address some of the basic scientific questions and future challenges in developing
these methods and technologies for general use in our society. We shall particularly emphasize the
use of High Intensity Focused Ultrasound (HIFU) in the treatment of benign and malignant tumors.
A review of the various clinical applications of HIFU will also be presented, as well as the existing
challenges to broad clinical acceptance of this technology.
Dr.Lawrence A. Crum is currently Principal Physicist in the Applied Physics Laboratory and Research Professor of Bioengineering and Electrical Engineering at the University of Washington.He has held previous positions at Harvard University, the U. S. Naval Academy and the University
of Mississippi, where he was F. A. P. Barnard Distinguished Professor of Physics and Director of
the National Center for Physical Acoustics. He has published over 300 articles in professional
journals, holds an honorary doctorate from the Universite Libre de Bruxelles, and was recently
awarded the Helmholtz-Rayleigh Silver Medal of the Acoustical Society of America. He is Past
President of the Acoustical Society of America and of the Board of the International Commission
for Acoustics. He is currently President of the International Society for Therapeutic Ultrasound.
Short Course 1B (1:00 P.M. - 5:00 P.M., Monday, October 11, 2010):
Course Title: Medical Ultrasound Transducers
Douglas G. Wildes, and L.Scott Smith, GE Global Research, Niskayuna, NY, USA.
Course Description: This course will provide an introduction to the design, fabrication, and testing of medical ultrasound transducers. Starting from an overview of the basic types of phased-array transducers (linear, convex, sector), we will discuss how the design for a probe is derived from its target application and how equivalent-circuit, finite-element, and acoustic field models can be used to optimize the design and accurately predict performance. A discussion of the structure of an ultrasound probe will lead to a survey of the different types of materials used in probes and their critical properties. Typical fabrication processes will be introduced and common problems in probe manufacturing will be summarized. Methods for evaluating completed transducers will be discussed. The course will highlight recent developments in probe technology, including single crystal piezoelectrics, cMUT transducers, catheters, 2D arrays, and electronics in probes, and will discuss performance advantages and fabrication difficulties which may be associated with each.
Douglas G. Wildes is a physicist with GE Global Research. He earned an A.B. in physics and mathematics from Dartmouth College and a Ph.D. in low-temperature physics from Cornell
University, then joined GE in 1985. Since 1991, Dr. Wildes’ research has focused on aperture
design, fabrication processes, and high-density interconnect technology for multi-row and 4D
imaging transducers for medical ultrasound. Dr. Wildes has 28 issued patents and 19 external
publications. He is a member of the American Physical Society and a Senior Member of the
IEEE.
Short Course 2B (1:00 P.M. - 5:00 P.M., Monday, October 11, 2010):
Course Title: Regulatory and Safety Issues in Medical Ultrasound
Jeffery Brian Fowlkes, University of Michigan, Peter A. Lewin, Drexel University, William D. O'Brien, Jr., University of Illinois, Urbana-Champaign, Shahram Vaezy, US Food and Drug Administration, and Keith A. Wear,US Food and Drug Administration
Course Description: : Many studies have demonstrated potential bioeffects associated with ultrasound exposure. In order to address safety as well as performance of medical ultrasound devices, the FDA has developed regulatory guidance for pre-clinical testing and evaluation, including establishing recommended levels regarding diagnostic ultrasound acoustic output. This course will consider legal and scientific foundations for the FDA acoustic output exposure levels. Topics will include basic medical device regulatory law, regulatory guidance, indexes of acoustic output, methods of and advances in measuring acoustic output, thermal bioeffects, mechanical bioeffects, and bioeffects associated with ultrasound contrast agents.
Jeffery Brian Fowlkes is a Professor of Radiology and Professor of Biomedical Engineering. He is currently directing and conducting research in medical ultrasound including the use of gas bubbles for diagnostic and therapeutic applications. His work includes studies of ultrasound contrast agents for monitoring tissue perfusion, acoustic droplet vaporization for bubble production in cancer therapy and phase aberration correction, effects of gas bubbles in high intensity ultrasound and volume flow estimation for ultrasonic imaging. Dr. Fowlkes received his B. S. degree in physics from the University of Central Arkansas in 1983, and his M. S. and Ph.D. degrees from the University of Mississippi in 1986 and 1988, respectively, both in physics. Dr. Fowlkes is a fellow of the American Institute of Ultrasound in Medicine and has served as Secretary and as a member of its Board of Governors. He also received the AIUM Presidential Recognition Award for outstanding contributions and service to the expanding future of ultrasound in medicine. As a member of the Acoustical Society of America, Dr. Fowlkes has served on the Physical Acoustics Technical Committee and the Medical Acoustics and Bioresponse to Vibration Technical Committee. As a Member of the IEEE, he has worked with the IEEE I&M Society Technical Committee on Imaging Systems. Dr. Fowlkes is a fellow of the American Institute of Medical and Biomedical Engineering.
Short Course 3B (1:00 P.M. - 5:00 P.M., Monday, October 11, 2010):
Course Title: Estimation and Imaging of Tissue Motion and Blood Velocity
Hans Torp and Lasse Lovstakken, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Course Description: This course provides a basic understanding of the physical principles and signal processing methods for estimation of blood flow velocity using ultrasound. The course begins with an overview of currently used techniques for velocity estimation using pulsed- and continuous-wave Doppler, and color flow imaging. Fundamental challenges related to data acquisition will be presented, and statistical models for the received signal as well as commonly used velocity estimators will be developed. The suppression of clutter from slowly moving targets is central to all techniques and will be given special attention. Further, an introduction to advanced topics such as adaptive clutter filtering and 2-D / 3-D vector velocity estimation techniques will be given, as well as an overview of the challenges and possibilities of using parallel acquisition techniques. Principles and practical limitations will be discussed, and potential clinical applications will be shown.
Hans Torp received the MS degree in mathematics in 1978, and the Dr. Techn. Degree in electrical engineering in 1992; both from the University of Trondheim, Norway. Since 1980 he has been working with ultrasound technology applied to blood flow measurements and imaging at the University of Trondheim, in cooperation with GE-Vingmed Ultrasound. He is currently professor of medical technology at the Norwegian Univesity of Science and Technology, and has since 1987 given courses on ultrasound imaging and blood flow measurements for students in electrical engineering and biophysics. His research interests include statistical signal- and image processing with application in medical ultrasound imaging.
Short Course 4B (1:00 P.M. - 5:00 P.M., Monday, October 11, 2010):
Course Title: Nonlinear Effects in SAW and BAW components
*Masanori Ueda, *Hiroshi Nakamura and **Ken-ya Hashimoto, *TAIYOYUDEN CO., LTD., JAPAN, **Chiba University, JAPAN.
Course Description: Requirements given to RF acoustic devices are becoming
stringent year by year. In addition to very low insertion loss and a steep cut-off
characteristic, reduction of the nonlinear products such as inter-modulation distortion
(IMD) and triple-beat products (TB) is vital for the use in the wideband code division
multiple access (WCDMA) or the third generation systems. Therefore, investigations of
nonlinear effects in SAW and BAW component, the reduction of acoustic device
nonlinearities becomes very important.This course provides 4 topics: a) basics on mechanical and electrical nonlinear effect
will be introduced. b) we will give a lecture how to evaluate nonlinearity on SAW/BAW
devices for high power applications and will point out some key points. c) nonlinear
performances of SAW and BAW resonators, the nonlinear simulation technique on BAW
devices, some verification for our proposed nonlinear simulation and some techniques to
reduce BAW nonlinear products will be introduced and discussed. d) influences of
nonlinear products in mobile systems and system specifications will be presented and
discussed.
Masanori Ueda was born in 1963 in Hokkaido, Japan. He received his B.S. and M.S.degrees in Material Engineering in 1986 and 1988, respectively, from Muroran Institute
of Technology, Japan, and he received his Dr. of Eng. degree in 2009 from Chiba
University, Japan.In 1988, he joined FUJITSU LIMITED. He was a director of FUJITSU MEDIA
DEVICES LTD. in 2003 and a research fellow of FUJITSU LABORATORIES LTD in
2008. He joined TAIYO YUDEN CO., LTD. in 2010, and is now a general manager of
microdevice R&D dept.He is involved in research and development of acoustic devices including surface
acoustic and film bulk acoustic filters and duplexers, and RF front-end module.
Dr. Ueda has authored or co-authored many papers and patents on acoustic devices.
He serves as a TPC member of the IEEE Ultrasonics Symposium and a member of
technical committee IEEE MTT-2 microwave acoustics, and is a member of the Institute
of Electronics, Information, and Communication Engineers of Japan.
Short Course 5B (1:00 P.M. - 5:00 P.M., Monday, October 11, 2010):
Course Title: Applications of High Frequency Ultrasonics in Microfluidics
James Friend, Monash University, Melbourne, Australia.
Course Description: The transmission of acoustic waves through materials and across interfacial-discontinuities is a centuries old area of research. A rather curious application of ultrasonic acoustic
radiation--actuation of fluids and particles within them--has renewed interest in this area and exposed
phenomena that are not explained by previous theories once viewed as canon. During the talk applications
of these phenomena will be proffered, including fingernail-sized microdevices to atomize sessile droplets for
drug encapsulation, pulmonary drug delivery and nanoparticle formulation; devices for droplet jetting and
manipulation; a device for fluid pumping and particle segregation in closed microfludics structures; and a
device to enable micro and nanoparticle concentration and separation in a sessile droplet in a matter of
seconds. These technologies indicate the potential for ultrasonics to deliver on the many idyllic promises of
microfluidics. Along the way, the underlying physical phenomena will be explored and explained, and the
potential future of this area will bring the course to a close. This course will offer an overview of ultrasonics
at small scales, including fabrication, piezoelectrics and fluid physics; proper analysis of ultrasonic &eld
propagation in viscous fluids at small scales incorporating nonlinear phenomena with a review of classical
terminology; and the many applications of the phenomena from fluid pumping and jetting to particle
separation and organic chemistry enhancement.
James Friend is a Professor in the Department of Mechanical and Aerospace Engineering and Associate Dean, Research for the Faculty of Engineering at Monash University, Melbourne, Australia, and received his B.Sci magna cum laude in aerospace engineering, M.Sci. and PhD in mechanical engineering from the
University of Missouri-Rolla in 1992, 1994 and 1998, respectively. He is the associate editor of
Biomicrofluidics, is a member of the IEEE Nanotechnology for Biology Committee, is on the advisory board of
the Lifeboat Foundation for safe uses of nanotechnology, and a founding academic member of the $60
million Melbourne Centre for Nanofabrication. From 2001 to 2004, Dr. Friend was an assistant professor at
the Precision and Intelligence Laboratory, Tokyo Institute of Technology. He joined Monash University in
late 2004, and co-founded and co-directs the $7.5 million MicroNanophysics Research Laboratory with
Associate Prof Leslie Yeo; the lab currently has a staff of three academics, three post-doctorates and thirteen
PhD students. He has over one hundred peer-reviewed publications, with five book chapters, fify-six peer-reviewed
journal papers, and sixteen patents and patent applications in progress. He received excellence in
teaching and early career researcher awards from the Monash Faculty of Engineering in 2007 and 2008,
respectively, a Future Leader award from the Davos Future Summit in Sydney in 2008, and was named as
one of the top 10 emerging scientific leaders of Australia by Micrososoft and The Australian newspaper in
2009.
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