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March 6, 2014

Mtg: Nano-Patterned Lipid Particles for Targeted Drug Delivery Therapeutics

by @ 1:25 pm. Filed under ALL, BioEngineering, NanoEngineering

WEDNESDAY March 19, 2014
SCV Engineering in Medicine and Biology Chapter
– self-assembly, nano-carrier, targeted delivery …
Speaker: Jayakumar Rajadas, Ph.D., Biomaterials and Advanced Drug Delivery Laboratory, Stanford Cardiovascular Pharmacology Division of Cardiovascular Institute
Time: Optional dinner at Stanford Hospital Cafeteria, 6:15 PM (no host, no reservations); Presentation at 7:30 PM
Cost: none (free parking after 4 PM)
Place: Presentation in Room M-114, Stanford University Medical School, Stanford
RSVP: not required

Lipids can self-assemble into higher-order functional structures such as membranes and vesicles.  Different combinations of lipids can develop into different-sized lipids particles.  When these particles interact with bio fluids such as blood and intestine secretions, they develop into structures of  desired patterns that can recognize endothelial linings of the blood capillaries that are proximal to the affected tissues.  This talk focuses on using such complex structures for the purpose of drug delivery to the heart, brain and liver.  At the Biomaterials and Advanced Drug Delivery laboratory at Stanford, we have developed a Nano-carrier combination platform, consisting of lipids and serum proteins, to develop novel structures that can recognize impaired heart and liver tissues.  For the first time, we have used this technology to stabilize fragile peptides, proteins and water-insoluble therapeutic molecules to target the delivery of these molecules to different organs.


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