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IEEE EMB Society Atlanta Chapter

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CHAIR
Chair: Dr. Philip FitzSimons
President, FitzSimons Automation, Inc.
(Business) 770-935-8649
www.fitzsimonsautomation.com
fitzsimo@mindspring.com

Other officers:
Vice-Chair: Dr Xiaoping Hu; Professor and Georgia Research Alliance, Endowed Eminent Scholar in Imaging, Coulter Department of Biomedical Engineering Georgia Tech and Emory University
Secretary: Chip Standifer, Vice President of Product Development at LifeSynch
Treasurer: Liang Guo, Ph.D Candidate at Georgia Tech

UPCOMING ACTIVITIES

You are invited to the next meeting of the Atlanta Chapter of the IEEE Engineering in Medicine and Biology Society. Information will be posted here when available.
Date:
Time:
Where:
Abstract:
Bio:
Directions:

Questions? Contact Dr. Philip FitzSimons (fitzsimo@mindspring.com)



PAST ACTIVITY
On January 28, 2010, Michael Sorensen, Ph.D. presented "How to solve math fast: low-cost, high-performance biophysical simulation on multi-core processors and GPUs." The multi-core revolution is over: 2, 4, or even 8-core workstations are now common for most technical computing professionals. The next revolution in computing is already beginning: massively multi-core hardware in which 100s of processor cores will be available. nVidia, Inc. has been leading the charge with the introduction of their CUDA architecture for general-purpose graphics processing unit (GPGPU) computing, and their Tesla series of GPGPU processors.

Effective multi-core programming is, however, still underutilized by most users, who have neither the technical background, time, or inclination to parallelize their code for these new architectures. Simatra's simEngine compiler is an application designed to automatically parallelize numerical simulations for multi-core and massively multi-core architectures. For scientists and engineers looking to create powerful numerical simulations with a minimal amount of coding, the simEngine platform provides an intuitive, flexible, and powerful workflow. Michael discussed the background of simEngine and how it can be used to provide performance gains over 300 times greater than a conventional single-core processor.

Michael Sorensen founded Simatra Modeling Technologies in 2006 with Randy Weinstein and Robert Lee from the Georgia Tech Laboratory for Neuroengineering. The IEEE EMB Society is grateful to Mr. Sorensen for giving this presentation.


On October 29, 2009, Joseph L. Long, Esq., P.E. spoke on "Intellectual Property for Scientists and Biomedical Engineers" He gave an overview of intellectual property issues of relevance to engineers, scientists, and managers. He began with a brief comparison of the different types of intellectual property including patents, copyrights, trademarks, and trade secrets. The remainder of the presentation focused predominantly on patents including the types of patents available, patentable subject matter, inventorship, and patent ownership. He continued with a discussion of patentability, the parts of a U.S. patent application, and a typical timeline and process for obtaining a patent in the United States.

Joseph Long (IEEE Senior Member) is a Patent Attorney with well over a decade of engineering experience. Joe is also licensed as a Professional Engineer by the State of Georgia, and is registered to practice before the United States Patent and Trademark Office. The IEEE EMB Society is grateful to Mr. Long for giving this presentation.


On August 25, 2009, Rafael V. Andino, President and CEO Biofisica, spoke on "Creating a New Venture in the Medical Device Industry". The talk discussed considerations that should be reviewed in the creation of a new medical device company. Topics included product development, market selection, development of a team, sales and marketing, manufacturing, and finance. The presentation aimed to give the audience an appreciation of the process and the general requirements necessary to build a successful medical device company from the ground up.

Mr. Andino founded Biofisica, Inc. in 1999 with the vision of developing breakthrough products to expedite wound healing and regeneration of connective tissue in humans. In late 2006, Mr. Andino and his management team launched the first wound care product of its kind, POSiFECT®, in the United Kingdom. The IEEE EMB Society is grateful to Mr. Andino for giving this presentation.


On January 13, 2009, Dr. Zhong Lin (Z.L.) Wang, Regents Professor at the School of Materials Science and Engineering, Georgia Institute of Technology, spoke on "Nanotechnology for energy harvesting: from nanogenerators to nanopiezotronics". Energy and technologies are desperately needed for independent and continuous operations of implantable biosensors, ultrasensitive chemical and biomolecular sensors, nanorobotics, micro-electromechanical systems, remote and mobile environmental sensors, homeland security and even portable personal electronics. A nanorobot, for example, is proposed to be a smart machine that may be able to sense and adapt to the environment, manipulate objects, taking actions and perform complex functions. A key challenge is to find a power source that can drive the nanorobot without adding much weight. An implanted wireless biosensor requires a power source, which may be provided directly or indirectly by charging of a battery. It is highly desired for wireless devices and even required for implanted biomedical devices to be self-powered without using battery. This talk focused on nanotechnologies that have been developed for harvesting energy from our living environment with a focus on mechanical energy. An introduction was given about nanogenerators for generating electricity using sonic waves and body movements. Finally, a new field on nano-piezotronics was introduced, which uses piezoelectric-semiconducting coupled property for fabricating novel and unique electronic devices and components.

Dr. Zhong Lin (ZL) Wang has authored and co-authored four scientific reference and textbooks and over 540 peer reviewed journal articles, 55 review papers and book chapters, edited and co-edited 14 volumes of books on nanotechnology, and holds 20 patents and provisional patents. Dr. Wang was in the world's top 25 most cited authors in nanotechnology from 1992-2002 (ISI, Science Watch). His entire publications have been cited over 23,000 times. The H-index of his citations is 73.

Dr. Wang discovered the nanobelt in 2001, which is considered to be a ground-breaking work. The paper on nanobelt was the second most cited paper in chemistry in 2001-2003 world-wide. His paper on piezoelectric nanosprings was one of the most cited papers in materials science in 2004 world-wide. His recent invention of world's first nanogenerator will have profound impacts to implantable biosensors and molecular machines/robotics. In 1999, he and his colleagues discovered the world's smallest balance, nanobalance, which was selected as the breakthrough in nanotechnology by the America Physical Society. He was elected to a fellow of American Physical Society in 2005, fellow of AAAS in 2006, has received the 2001 S.T. Li prize for Outstanding Contribution in Nanoscience and Nanotechnology, the 2000 and 2005 Georgia Tech Outstanding Faculty Research Author Awards, Sigma Xi 2005 sustain research awards, Sigma Xi 1998 and 2002 best paper awards, and the 1999 Burton Medal from Microscopy Society of America. Details can be found at: http://www.nanoscience.gatech.edu/zlwang
The IEEE EMB Society is grateful to Dr. Wang for giving this presentation.


On October 28, Dr Maysam Ghovanloo, assistant professor in the School of Electrical and Computer Engineering at Georgia Tech, spoke on "Novel technologies to improve the quality of life for individuals with disabilities."

Maysam Ghovanloo is director of the Georgia Tech Bionics Laboratory (GT-Bionics), which has a goal of enhancing the state-of-the-art by developing new implantable microelectronic devices and novel assistive technologies. Details about Dr. Ghovanloo's research projects can be found at: http://www.ece.gatech.edu/research/labs/gt-bionics/index_files/My_Research.htm
The IEEE EMB Society is grateful to Dr. Ghovanloo for giving this presentation.


On August 27, 2008, Dr Srini Tridandapani presented "Freezing the Heart: A Proposal for Research in Cardiac Computed Tomographic Angiography".

Cardiac computed tomography (CT), particularly CT coronary angiography, is at the cusp of revolutionizing cardiac diagnosis. The chief challenge is that CT slices need to be acquired during the portion of the cardiac cycle where the heart is quasi-stationary or quiescent. This has thus far been limited because the current solution -electrocardiography (ECG)-based gating, does not accurately and reliably predict the instantaneous position of the heart. Dr Tridandapani believes that echocardiography or ultrasound (US), a real-time modality just like ECG, can provide a better trigger since it actually images the exact position of the heart. He proposed to 1) prove that US is superior for this purpose, and 2) develop a real-time US-based trigger for purposes of CT slice acquisition. The ultimate expected outcome of this development would be a reduction in the number of normal, diagnostic, invasive coronary angiograms.

Dr. Tridandapani is in the embryonic stages of building a laboratory to develop advanced cardiac imaging techniques. The IEEE EMB Society is grateful to Dr. Tridandapani for giving this presentation.


On April 1, 2008, Dr. Julian Alexander Bragg presented "From Engineering to Medicine: Threshold Tracking". While the majority of medical school applicants still enter with a degree in life sciences, a small but significant number of them have an engineering background. An engineering education, with its training in systems-level thinking and problem solving despite incomplete information, provides a solid intellectual base for both clinicians and clinician-scientists. One recent example of applying engineering techniques to clinical problems is the development of threshold tracking techniques for studying the excitability of peripheral nerves. While conventional nerve conduction studies measure only the nerve's conduction velocity and maximum response amplitude, threshold tracking allows noninvasive determination of nerve excitability and how that excitability changes with exposure to various stimuli. These techniques are being investigated by multiple groups in hopes that they will serve as more sensitive indicators of nerve dysfunction for diagnostic purposes and also clarify the electrophysiologic abnormalities underlying various peripheral nerve disorders.

Dr. Bragg's current research interests include the use of threshold tracking techniques to noninvasively measure peripheral nerve excitability and the use of stimulus artifact elimination techniques to improve the quality and versatility of neuromuscular electrodiagnostics. The IEEE EMB Society is grateful to Dr. Bragg for giving this presentation.


On January 29, 2008,IEEE-EMBS Distinguished Lecturer Dr. Yongmin Kim presented on "Electronic House Calls: High-Tech Medicine at Your Doorstep" on the Georgia Tech Campus. The traditional healthcare system is characterized by hospital or clinic-based face-to-face contacts between the patient and care provides, which frequently occur at times and locations that are inconvenient or difficult for the patient. The healthcare delivery in the future needs to be provided in a distributed, patient-centered manner. The distributed diagnosis and home healthcare (D2H2) will benefit patients, particularly those with chronic disease, e.g., diabetes, arthritis, and high blood pressure, by improving the quality, convenience and efficiency of care, reducing the healthcare cost, and preventing medical errors, thus leading to increasing access to affordable and effective healthcare. There are many opportunities for engineers and scientists to innovate and contribute to this 21st century healthcare system.

Dr. Kim's biographical information is available online at Dr. Kim's bio
The IEEE EMB Society is grateful to Dr. Kim for giving this presentation.


On Thursday November 8, 2007 Dr. Pamela Bhatti, Assistant Professor, School of ECE, Georgia Tech spoke on Cochlear Implants: Past, Present and Future. Dr. Bhatti’s current research interests are in the general area of biomedical sensors and subsystems, bioMEMS, and microelectronics. Specifically, she is interested in implantable cochlear electrode arrays, vestibular prostheses, and the integration of controlled-release drug delivery technology with flexible neural recording/ stimulating arrays.

Her speech gave a description of the ear and the function of cochlear implants, explaining that they are only used in patients with hearing loss in both ears. She briefly described the past and present of cochlear implants. Present systems typically use signals at several megahertz to communicate from external microphone circuitry to the receiver implanted in the cochlea and to power the implant. Post-surgery capabilities exist for Neural Response Telemetry which helps determine how the nerve is responding to the implant. The largest company is Cochlear Limited in Australia, and names used here are their device names. The other manufacturers (MedEl and Advanced Bionics) have similar devices. Dr. Bhatti said that the future of hearing improvement may include items from the following list that are either enhanced uses of devices that are already approved for usage or new research devices. These include:
- improvements in Electro-Acoustic stimulation to keep the patients low frequency hearing and supplement it by improving their high frequency hearing;
- improvements in BAHA Bone Anchored Hearing Aids;
- improvements in ABI Auditory Brainstem implants which connect directly to the auditory nerve;
- developing TIKI Totally Implantable Cochlear Implants;
- developing cochlear hair cell repair;
- and developing neurotropin delivery for treatment of neuron damage affecting the inner ear.

The EMBS Atlanta chapter is grateful to Dr. Bhatti for taking the time to give us her presentation.


On Thur Aug 2, 2007 we held a "planning/brainstorming" meeting for the Atlanta IEEE-EMBS chapter. We discussed possibilities of job fairs, lab tours, student activities, local outreach to K-12, hosting a regional biomedical engineering meeting, organizing a future meeting around the topic of "Building Bridges Between Clinicians and Engineers," and scheduling an expert speaker funded by the IEEE.


On April 23, 2007 Dr. Bill Hunt, Professor, School of ECE, Georgia Tech spoke about Acoustic Wave Biosensors for Molecular Recognition and Detection of Conformational Change. The presentation was given at Southern Polytechnic University.
Acoustic wave devices coated with a biolayer represent one biosensor approach for the detection of medically relevant biomolecules. In a typical application, the acoustic wave device is connected in an oscillator circuit, and the frequency shift Delta-f resulting from a biomolecular event is recorded. Work has included the use of Rayleigh wave surface acoustic wave devices for vapor phase detection as well as ZnO resonators and quartz crystal microbalance devices for liquid phase measurements. For most of the results presented the biofilm on the surface of the acoustic wave device consists of a layer of antibodies raised against a specific target molecule or antigen. Results were presented for the vapor phase detection of small molecules such as uranine, cocaine, TNT and RDX as well as liquid phase detection of small proteins, lipids and DNA. The data from these various experiments is the signature associated with the biomolecular recognition events; that is, Delta-f(t). Also presented were the results of the time-dependent perturbation theory work, which gives a potential method for resolving the acoustic wave biosensor signature into information relating to molecular structure changes during a molecular recognition event.
The IEEE EMB Society is grateful to Dr. Hunt for giving this presentation.


On Mon January 29, 2007, Dr. Rosana Esteller talked about recent developments in neural stimulation for control of epilepsy advanced by Neuropace. Dr. Esteller holds a Ph.D. in Electrical and Computer Engineering from Georgia Tech. She is currently employed by Neuropace, a company founded to design, develop, manufacture and market implantable devices for the treatment of neurological disorders by responsive brain stimulation. Information about Neuropace can be found at www.neuropace.com. The IEEE EMB Society is grateful to Dr. Esteller for giving this presentation.


On October 30, 2006, Dr. Melody Moore Jackson, Director, Georgia Tech BrainLab Graphics, Visualization, and Usability Center, College of Computing, Georgia Institute of Technology spoke about Direct Brain Interfaces: Communicating with Brain Signals. A Direct Brain-Computer Interface (DBI) is a system that detects minute electrophysiological changes in brain signals, and uses them to provide a channel to control computers and other devices. For people with severe physical disabilities, such as locked-in syndrome and the aftermath of strokes, DBIs can offer a channel of communication that does not depend on muscle movement. The BrainLab is devoted to exploring the possibilities of real-world applications for DBI and other biometric interfaces, both for assistive technology and mainstream applications. Dr. Jackson outlined several approaches to both invasive (surgically implanted) and non-invasive (non-surgical) DBIs, and presented the assistive technology systems that the BrainLab is currently researching.
The IEEE EMB Society is grateful to Dr. Jackson for giving this presentation.


On Aug 1, 2006 at the Chamblee Branch of Dekalb Public Library, the inaugural meeting of the IEEE EMB Society Atlanta chapter was held. Michael Fonseca, Director, MEMS Operations, CardioMEMS spoke about the technology and products behind CardioMEMS.
CardioMEMS is an Atlanta-based medical device company that makes wireless pressure sensors. This past year they received FDA marketing approval for their first product.
More info is at http://www.cardiomems.com
The IEEE EMB Society is grateful to Michael for giving this presentation.



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