IEEE Engineering in Medicine and Biology
Society (EMBS) is the world's largest
international society of biomedical engineers. EMBS provides its members with
access to the people, practices, information, ideas and opinions that are
shaping one of the fastest growing fields in science.
You are invited to the next meeting of the Atlanta Chapter of the IEEE
Engineering in Medicine and Biology Society.
- Title: Next Generation Strategies to Refine and Optimize DBS for
- Speaker: Dr. Helen Mayberg; Professor of Psychiatry, Neurology, and
Radiology and the Dorothy Fuqua Chair in Psychiatric Imaging and Therapeutics;
Emory University School of Medicine
- Date: Thursday, September 14, 2017
- Time: 6:30pm-8:00pm, dinner at 6:30pm, speaker at 7:00pm
- Location: GTRI Conference Center, Room 119A, 250 14th St NW, Atlanta,
- Parking: Free parking available on-site
- RSVP: Register via IEEE
vtools (IEEE Membership not required)
- Abstract: Deep Brain Stimulation (DBS) is an emerging treatment strategy
for patients with intractable depression with selection of the subcallosal
cingulate (SCC) as a stimulation target based principally on converging
findings from resting-state PET studies of conventional antidepressant
interventions. At present, surgical implantation of DBS electrodes relies on
high resolution structural images to localize the SCC grey matter-white matter
border followed by trial-and-error behavioral testing of chronic stimulation at
individual contacts. Clinical response may however be optimized by more precise
targeting along specific white matter tracts as evidenced by recent diffusion
tensor imaging and tractography analyses of DBS responders and non-responders.
Catalyzed by availability of next generation devices that allow ongoing
recordings of local field potentials in the targeted circuit of interest,
recent work now combines multimodal neuroimaging with real-time behavioral and
electrophysiological measurements, providing a more precise method to identify
the optimal target location and stimulation parameters for individual patients.
Strategic integration of neuroengineering innovations and selective animal
models offers potential complementary perspectives to fully delineate critical
pathways and mechanisms mediating antidepressant effects of SCC DBS and inform
on the pathophysiology of treatment resistant depression more generally.
- Bio: Helen Mayberg, MD is Professor of Psychiatry, Neurology and
Radiology, and the Dorothy Fuqua Chair in Psychiatric Imaging and Therapeutics
at Emory University. Her research has characterized neural systems mediating
major depression and its recovery, defined imaging-based illness subtypes to
optimize treatment selection, and introduced the first use of deep brain
stimulation for treatment resistant patients. Dr. Mayberg received a BA in
Psychobiology from UCLA and a MD from University of Southern California, and
then completed her neurology residency at the Neurological Institute of New
York, and fellowship training in nuclear medicine at Johns Hopkins. She is a
member of the National Academy of Medicine, the National Academy of Arts and
Sciences, and the National Academy of Inventors, and has authored more than 200
publications, and participates in a wide variety of advisory and scientific
activities across multiple fields in neuroscience.
- Chair: Martha Willis
Biomedical Technology Industry Programs,
Translational Research Institute for Biomedical Engineering and Science, The
Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and
- Vice-Chair: Adriane Swalm Durey, Ph.D.
Staff Engineer, Software,
- Secretary: Philip FitzSimons, Ph.D.
- Treasurer: Jacqueline Fairley, Ph.D.
Georgia Tech Research
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