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Engineering in Medicine and Biology Society



Santa Clara Valley Chapter Monthly Meeting


SCV EMBS Meetings are usually scheduled for the third Wednesday of each month, except July, August, and December. The formal presentation is 7:30 - 8:30 pm. Afterwards, there is an opportunity to network.

The usual meeting location is in Room M114 of the Medical School on Stanford Campus. M114 is in the corner closest to the Clark Bioscience Building.



Meet the Speaker
An optional, no-host dinner with the speaker precedes each meeting, and you are invited. We gather in the Stanford Hospital cafeteria at 6:15 pm. No reservation is needed.


Upcoming EMBS Meeting
February 20, 2019, 7:30 PM
Room M-114, Alway Building, Stanford University Medical School

Title: Real-time Biosensors for continuous measurements of specific biomolecules in live animals
Speaker: Dr. H. Tom Soh
Professor of Electrical Engineering and Radiology at Stanford University

Abstract:
A biosensor capable of continuously measuring specific molecules in the bloodstream in vivo would give clinicians a valuable window into patients' health and their response to therapeutics. Unfortunately, continuous, real-time measurement is currently only possible for a handful of targets (i.e. glucose, and oxygen) and existing platforms for continuous measurement are not generalizable for the monitoring of other analytes. In this talk, we will present a universal real-time biosensor technology capable of continuously tracking a wide range of circulating molecules in living animals. Our real-time biosensor requires no exogenous reagents and can be readily reconfigured to measure different target molecules by exchanging molecular probes in a modular manner. Next, we will present the first real-time, closed loop feedback control of drug concentration in live animals using the real-time biosensor, and discuss potential applications of our technology. Finally, we will discuss methods for generating synthetic molecular probes (aptamers) that are at the heart of these biosensor technologies.

Biography:
Dr. H. Tom Soh is a Professor of Electrical Engineering and Radiology at Stanford University. His laboratory develops synthetic biomaterials and biosensor devices. He earned his B.S. (1992), with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University and his M.S. (1995) and Ph.D. (1999) in Electrical Engineering from Stanford University. Between 1999 and 2003, he served as a technical manager of MEMS device research group at Bell Laboratories and Agere Systems. Between 2003 and 2015, he was the Ruth Garland Professor at UC-Santa Barbara (UCSB) in the department of Mechanical Engineering and Materials. His lab moved to Stanford in 2015. He is a recipient of numerous awards including MIT Technology Review's "TR 100" Award, ONR Young Investigator Award, Beckman Young Investigator Award, ALA Innovator Award, NIH Director's TR01 Award, NIH Edward Nagy Award, Guggenheim Fellowship, and Alexander van Humboldt Fellowship. Dr. Soh is a Chan-Zuckerberg Biohub Investigator, fellow of the American Institute for Medical and Biological Engineering (AIMBE), and member of the National Academy of Inventors (NAI).




Parking at Stanford
Parking is available in the structure at the corner of East Campus Drive and Roth Way. Parking is free after 4pm.
Parking is also available in the Stanford hospital parking structure off Pasteur Drive and Blake Wilbur Drive, but there is a fee.


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