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Abstract

Grant Number: 1R43CA094385-01
PI Name: ENTINE, GERALD
PI Email: gentine@rmdinc.com
PI Title: PRESIDENT
Project Title: High Resolution, Low Cost PET Module

Abstract: DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) has become an important tool in the fight against cancer. PET is now being used in diverse studies ranging from basic research in animal models of cancer in the mouse, through to diagnosis and staging of cancer patients in the clinic. It is clear that PET technology is playing a prominent and an increasingly visible role in modem cancer research and clinical diagnosis. However, there is an urgent need for improvement in PET instrumentation in order to exploit full potential of this promising technique. In order to address the limitations in the existing detector technology used in PET systems, particularly the photomultiplier tubes used for optical readout of scintillators, we propose to investigate a novel, solid state position sensitive optical detector technology. This new optical detector technology can be used to build high resolution PET modules, which can be utilized in PET systems suitable for clinical whole body imaging as well as dedicated, high resolution systems for breast and small animal imaging. The proposed Phase I project will aim to demonstrate the feasibility of this concept.

Thesaurus Terms:
biomedical equipment development, monitoring device, optics, positron emission tomography
electrode, electromagnetic radiation, imaging /visualization /scanning, neoplasm /cancer diagnosis, photomultiplier
bioengineering /biomedical engineering

Institution: RADIATION MONITORING DEVICES, INC.
44 HUNT ST
WATERTOWN, MA 02472
Fiscal Year: 2002
Department:
Project Start: 12-JUN-2002
Project End: 11-JUN-2004
ICD: NATIONAL CANCER INSTITUTE
IRG: ZCA1


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