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| Grant Number: | 5R44HG001893-03 |
| PI Name: | CASSEL, CAROLYN F. |
| PI Email: | carolyn@dnastar.com |
| PI Title: | |
| Project Title: | SUPERIOR SOFTWARE FOR LARGE-SCALE DNA FRAGMENT ASSEMBLY |
Abstract: APPLICANT?S DESCRIPTION: This proposal presents a plan to design and produce a software product for DNA fragment assembly that meets the needs of large-scale sequencing efforts. The effort demands software that is fast and highly accurate. DNASTAR?s proposed product will meet the needs through the development of new fragment assembly software that incorporates a novel linear-time algorithm extended to handle myriad fragment reads; a highly accurate consensus-caller; efficient methods for handling repeats; access to databases; full use of fragment reads; base call quality scores; and physical map constraints. The combination will form a unique package of the fastest, most accurate, and most flexible software available for DNA sequencing. PROPOSED COMMERCIAL APPLICATION: Not Available
Thesaurus Terms:
computer assisted sequence analysis, computer program /software, computer system design /evaluation, nucleic acid sequence
DNA, nucleic acid repetitive sequence, statistics /biometry
| Institution: | DNASTAR, INC. |
| 1228 S PARK ST | |
| MADISON, WI 53715 | |
| Fiscal Year: | 2002 |
| Department: | |
| Project Start: | 01-JAN-1999 |
| Project End: | 31-DEC-2003 |
| ICD: | NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
| IRG: | ZRG1 |