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Abstract

Grant Number:	1R43AG022280-01
PI Name:	XU, XUEYAN
PI Email:	sxu@clevemed.com
PI Title:
Project Title:	A Brain Computer Interface for Disabled Individuals

Abstract: DESCRIPTION (provided by applicant): The specific aim of this project is to develop a compact, convenient, and easy-to-use wireless brain-computer interface (BCI) system that allows limited but extremely valuable communications with the most severely head injured patients using their brain wave. The hardware components include a miniature 8-channel (19 or 38-channel) transmitter capable of acquiring, amplifying, digitizing, and transmitting EEG/ERP signal, a receiver that is attached to a commercial PC, and a laptop PC, which can be easily fitted in a typical laptop PC case. A software package is developed for delivering user defined auditory/visual stimuli, acquiring and extracting ERPs, and classifying ERPs corresponding to each stimulus continuously in real-time. The primary challenge of this project is to classify match/mismatch event related potential (ERP) accurately and in real-time. An innovative multi-domain dense array neuroinformatic methodology is developed to classify the ERPs. Results from the preliminary study clearly show the feasibility of real-time classifying match/mismatch ERPs at high accuracy. The proposed brain-computer interface system will be evaluated in normal subjects during this phase I study. Successful implementation of the BCI system could have clinical significance by setting up a communication channel between physician and the severely injured patients and practical use.

Thesaurus Terms:
brain electrical activity, brain injury, communication disorder aid, computer human interaction, computer system design /evaluation, portable biomedical equipment
auditory stimulus, evoked potential, functional ability, personal computer, quality of life, visual stimulus
clinical research, electroencephalography, human subject, informatics, medical rehabilitation related tag, telemetry

Institution:	CLEVELAND MEDICAL DEVICES, INC.
	11000 CEDAR AVE, STE 130/461
	CLEVELAND, OH 44106
Fiscal Year:	2003
Department:
Project Start:	30-SEP-2003
Project End:	28-FEB-2004
ICD:	NATIONAL INSTITUTE ON AGING
IRG:	ZRG1

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