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Abstract

Grant Number:	1R43CA094540-01A1
PI Name:	MARYANSKI, MAREK J.
PI Email:	mgsinc1@mindspring.com
PI Title:
Project Title:	2-Phase Nanogels for Quantitative 3D Radiation Dosimetry

Abstract: MGS Research has pioneered the development of polymer gel dosimeters, using both MRI and optical CT scanning. Our goal in Phase I will be to prove the feasibility of an innovative two-phase nanostructured polymer gel for quantitative 3D radiation dosimetry. The new gel structure can be described as a "single-hit 3D photon counter" that can be expected to be linear with dose and to be dose-rate independent. Moreover, it will be characterized by greater reproducibility, accuracy and stability of the dose response. As a result, the nanostructured polymer gels will be more suitable than the existing single-phase gels for the quantitative 3D radiation dosimetry and high-precision quality assurance, which are very much needed in intensity modulated and 3D conformal radiation therapy.

Thesaurus Terms:
gel, polymerization, radiation dosage, technology /technique development
free radical scavenger, hydropathy, micelle, monomer, surfactant
nanotechnology

Institution:	MGS RESEARCH, INC.
	BOX 581, 47 CLAPBOARD HILL RD #2
	GUILFORD, CT 06437
Fiscal Year:	2003
Department:
Project Start:	01-SEP-2003
Project End:	31-AUG-2005
ICD:	NATIONAL CANCER INSTITUTE
IRG:	ZRG1

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