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Abstract

Grant Number:	1R43DC005951-01
PI Name:	MONTGOMERY, STUART K.
PI Email:	smontgomery@bosmed.com
PI Title:
Project Title:	Development of a Laryngeal stent for chronic aspiration

Abstract: DESCRIPTION (provided by applicant): Development of a new type of laryngeal stent is proposed. This implant is intended to provide treatment for chronic laryngeal aspiration, a severe medical condition that kills up to 50,000 patients each year. The current treatments or chronic aspiration are often not effective and can be devastating to the patients and their families. The proposed implant has significant potential to provide an improved method of treatment for chronic aspiration. The initial laryngeal stent design will prevent aspiration by closing off the larynx and redirecting saliva and food to the esophagus. The stent will be designed anatomically so as to seal the area of aspiration, while providing a natural and comfortable fit for the patient. Later designs (phase II) will incorporate a vertical lumen through the stent and a one-way valve system on the superior end. This, when coupled with a tracheal T-tube and external valve (currently commercially available), will allow the patient to regain speech. We propose to optimize (1) the anatomical design of the stent, and (2) the ability of the stent to stop chronic aspiration, so as to firmly establish it's scientific, technical, and commercial feasibility.

Thesaurus Terms:
biomaterial development /preparation, biomedical equipment development, implant, larynx, prosthesis, pulmonary respiration
biopsy, computed axial tomography, endoscopy, human tissue, medical implant science

Institution:	BOSTON MEDICAL PRODUCTS, INC.
	117 FLANDERS RD
	WESTBOROUGH, MA 01581
Fiscal Year:	2003
Department:
Project Start:	01-JAN-2003
Project End:	31-DEC-2003
ICD:	NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
IRG:	ZRG1

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