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Abstract

Grant Number:	1R43DK061279-01A1
PI Name:	KYNOR, DAVID B.
PI Email:	dbk@creare.com
PI Title:
Project Title:	Morphological Lesion Detection in CT Colonography

Abstract: DESCRIPTION (provided by applicant): Colorectal cancer is the second leading cause of cancer death in industrialized nations. Current screening techniques lack sufficient sensitivity or are expensive and require patient sedation. This project aims to develop a new set of tools to assist physicians in detecting cancerous lesions using CT colonography, a new screening technique that is fast and painless for the patient. The tools are based on the concept of a computerized detection algorithm to serve as a backup reader whose primary goal is to make sure that the clinician is alerted to suspicious lesions. The detection algorithm has been designed to be fast, sensitive and specific--capable of detecting polyps that are often missed using present techniques because they are buried on folds of the colon. The tools developed under this program may also assist the clinician in subtyping lesions and will provide a powerful research tool for quantifying lesion growth over time.

Thesaurus Terms:
colon disorder, colon neoplasm, computed axial tomography, computer system design /evaluation, diagnosis design /evaluation, gastrointestinal imaging /visualization, image processing, neoplasm /cancer diagnosis
computer data analysis, computer program /software, diagnosis quality /standard, mathematics
bioimaging /biomedical imaging, clinical research, human data

Institution:	CREARE, INC.
	BOX 71, ETNA RD
	HANOVER, NH 03755
Fiscal Year:	2003
Department:
Project Start:	15-MAR-2003
Project End:	28-FEB-2005
ICD:	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
IRG:	ZRG1

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