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Abstract

Grant Number:	1R43DK063732-01
PI Name:	KYNOR, DAVID B.
PI Email:	dbk@creare.com
PI Title:
Project Title:	Gastrointestinal Transit Measurement System

Abstract: DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly detailed recordings needed to fully evaluate patients. The goal of this project is the development of a new technique for outpatient measurement of gastrointestinal transit in patients with motility disorders. The technique captures the fine details of gastrointestinal transit, does not involve radiation, and is capable of making recordings for extended periods while patients undergo their daily routines. In Phase I of this project, a prototype of the Gastrointestinal Transit Measurement System (GTMS) will be constructed and tested in the laboratory. Testing will concentrate on determining the accuracy of the capsule tracking system and the ability of the system to capture transient movements. In Phase II, clinical demonstration testing will be conducted on volunteer subjects with normal and abnormal gastrointestinal function.

Thesaurus Terms:
biomedical equipment development, diagnosis design /evaluation, gastrointestinal absorption /transport, gastrointestinal disorder diagnosis, gastrointestinal imaging /visualization, gastrointestinal motility /pressure
image processing, three dimensional imaging /topography
bioimaging /biomedical imaging

Institution:	CREARE, INC.
	BOX 71, ETNA RD
	HANOVER, NH 03755
Fiscal Year:	2003
Department:
Project Start:	01-FEB-2003
Project End:	31-JUL-2004
ICD:	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
IRG:	ZRG1

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