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Abstract

Grant Number:	1R43EB000133-01A2
PI Name:	ARODZERO, ANATOLI
PI Email:	zrodzero@contech.com
PI Title:
Project Title:	High Resolution Gamma Camera

Abstract: DESCRIPTION (provided by applicant): A pixilated, solid-state, high-resolution Positron Emission Tomography (PET) detector with individual readout for each pixel and higher efficiency for 511 keV photons than currently available PET detectors will be developed. Recent improvements in Constellation's mercuric iodide detector technology have lead to the production of 10 mm-thick detectors and pixilated detectors, which also provide depth-of-interaction information. Intrinsic spatial resolution of 1 mm is now possible with these new mercuric iodide detectors while retaining high efficiency. Increased spatial resolution is particularly important in the application of PET imaging to smaller living systems (e.g. mice used in research labs) or to detect smaller lesions (e.g. small tumors). Mercuric iodide detectors also provide improved spectral resolution by allowing discrimination between the two types of full energy events; photoelectric events deposit all of their energy in a single location while Compton scattering followed by absorption deposits the energy in multiple locations. Phase 1 results will demonstrate the feasibility and performance of the new detector technology. In Phase 2, a prototype coincidence detector will be constructed for clinical evaluation.

Thesaurus Terms:
biomedical equipment development, image enhancement, positron emission tomography, scintillation camera
bioimaging /biomedical imaging

Institution:	CONSTELLATION TECHNOLOGY CORPORATION
	7887 BRYAN DIARY RD, STE 100
	LARGO, FL 33777
Fiscal Year:	2003
Department:
Project Start:	01-SEP-2003
Project End:	31-AUG-2004
ICD:	NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
IRG:	ZRG1

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