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Abstract
Grant Number: 1R43EB000976-01 PI Name: SAXENA, INDU PI Email: sbirproposals@intopsys.com PI Title: SENIOR SCIENTIST AND GROUP LEADER Project Title: Optical Signal Enhancement in Microcavity Resonators Abstract: DESCRIPTION (provided by applicant): Intelligent Optical Systems, Inc. (lOS) proposes to develop an innovative, optical fiber probe, or optode, that will improve collection efficiency of the probe by an order of magnitude and improve the sensitivity of target molecule sensing and imaging devices in medical applications. By fabricating submicron structures in glass, we will enhance optical signals in microcavity structure optodes. The proposed approach combines the usual fluorescent fiber optode detector with two new techniques: microcavity structures and alternating index clad fiber. This optode design increases the amount of light seen by the detector. Such an effect is achieved by the ability of periodic dielectric microcavity structures to modify the radiation properties of light inside the structure.
Thesaurus Terms:
biomedical equipment development, fiber optics, fluorescent dye /probe, monitoring device, photoconduction
polymer
bioengineering /biomedical engineering, bioimaging /biomedical imaging
Institution: INTELLIGENT OPTICAL SYSTEMS, INC. 2520 W 237TH ST TORRANCE, CA 905055217 Fiscal Year: 2003 Department: Project Start: 01-APR-2003 Project End: 31-MAR-2004 ICD: NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING IRG: ZRG1
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