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Abstract

Grant Number:	1R43EB001600-01
PI Name:	UFER, STEFAN
PI Email:	ufer@premitec.com
PI Title:
Project Title:	Non-enzymatic glucose sensor with novel electrocatalysts

Abstract: DESCRIPTION (provided by applicant): We propose the development of a non-enzymatic electrochemical glucose sensor based on alloy catalysts. These catalysts allow the direct oxidation of glucose at an electrode surface without the use of any mediators or enzymes. Thin film deposition and microfabrication technologies will be utilized to fabricate electrodes with electrocatalytic surfaces for amperometric glucose detection. A complete electrochemical evaluation will be performed with and without the presence of common interferents in physiological environments. The electrodes will be fabricated on rigid as well as flexible substrates, having dimensions small enough for in vivo applications. A photodefinable polyimide layer, spin coated and patterned using UV lithography will define the electrochemically active electrode areas.

Thesaurus Terms:
alloy, artificial endocrine pancreas, biomedical equipment development, biosensor, catalase, electrochemistry
glucose oxidase, lead, microelectrode, platinum, ultraviolet radiation
bioengineering /biomedical engineering, chemical synthesis

Institution:	PREMITEC, INC.
	920 MAIN CAMPUS DR
	RALEIGH, NC 27606
Fiscal Year:	2003
Department:
Project Start:	15-JUL-2003
Project End:	31-DEC-2003
ICD:	NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
IRG:	ZRG1

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