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Abstract
Grant Number: 1R43EY014754-01 PI Name: SARVER, EDWIN J. PI Email: ejsarver@aol.com PI Title: CONSULTANT Project Title: Multi-Resolution Corneal Topography (MRCT) Abstract: DESCRIPTION (provided by applicant): Objective: Develop a new reflection-based corneal topographer that provides more reliable and accurate measurements of the anterior corneal surface than those of commercially available systems. Specific Aims: Determine the feasibility of the multi-resolution corneal topograher (MRCT) by: (1) developing prototype color multiple-resolution reflection target, optical breadboard, and prototype software; (2) integrating components; and (3) evaluating the performance of the system. Health Relatedness: Provide more accurate anterior surface measurements needed for research and vision intervention techniques that correct higher-order aberrations. Methods: The project incorporates a novel reflection target design, reconstruction algorithm, and a high resolution digital camera. We refer to this new system as the multiple-resolution corneal topographer (MRCT) because the reflection target employs color sinusoidal profiles that provide three simultaneous multiple-resolution ring images. Technological Innovation: The MRCT system represents a new way of measuring the anterior corneal surface that will be more robust and accurate than other commercially available corneal topography systems. Our approach is a technological innovation over traditional reflection target methods in that it incorporates a color sinusoidal ring target to acquire multiple-resolution ring images (4, 16, and 64 rings) in a single exam.
Thesaurus Terms:
computer assisted diagnosis, cornea disorder, diagnosis design /evaluation, digital imaging, eye disorder diagnosis
computer program /software, computer system design /evaluation, computer system hardware
bioimaging /biomedical imaging
Institution: SARVER AND ASSOCIATES, INC. 3425 SAVANNAHS TRAIL MERRITT ISLAND, FL 32953 Fiscal Year: 2003 Department: Project Start: 01-MAR-2003 Project End: 31-AUG-2003 ICD: NATIONAL EYE INSTITUTE IRG: ZRG1