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Abstract

Grant Number:	2R44EY012320-02A1
PI Name:	KYNOR, DAVID B.
PI Email:	dbk@creare.com
PI Title:
Project Title:	Three-Dimensional Ocular Imaging Using Ultrasound

Abstract: DESCRIPTION (provided by applicant): The goal of this project is development of an ultrasonic imaging array capable of providing detailed images of the anterior segment of the eye. The array will be used to create anatomic images used for sizing of intraocular lens implants and treating pathological conditions, as well as pachymetric and topographic maps used in refractive surgery. During Phase I, we fabricated prototype transducer elements and demonstrated that the elements had sufficient sensitivity to detect the anterior and posterior corneal surfaces and Bowman's membrane in an ex vivo bovine eye. In Phase II, we plan to fabricate a complete two-dimensional imaging array and test the array on acoustic phantoms, rabbit eyes, and human eyes provided by the eye bank. Testing on animal and human eyes will be conducted by our clinical collaborators at the Weill Medical College of Cornell University. We will also work with our commercialization partner to integrate our array into their ocular imaging system.

Thesaurus Terms:
eye, technology /technique development, three dimensional imaging /topography, ultrasound
eye disorder diagnosis, eye refractometry
bioimaging /biomedical imaging, human tissue, laboratory rabbit

Institution:	CREARE, INC.
	BOX 71, ETNA RD
	HANOVER, NH 03755
Fiscal Year:	2003
Department:
Project Start:	05-AUG-1999
Project End:	31-AUG-2005
ICD:	NATIONAL EYE INSTITUTE
IRG:	ZRG1

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