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Abstract

Grant Number:	2R44HL065166-02A1
PI Name:	KRAUSMAN, DAVID T.
PI Email:	davek@imsystems.net
PI Title:	VICE PRSIDENT & CEO
Project Title:	Ambulatory Airflow-Pressure Monitor for Sleep Medicine

Abstract: DESCRIPTION (provided by applicant): The problems in sleep medicine caused by the cost; access and variety of sleep laboratory testing have led to increasing use and demand for home testing particularly for evaluation of suspected sleep apnea. The definition of sleep-related breathing disorders (SRBD) has, however, expanded to include flow-limited breathing events. Assessment of these events and of hypopneas requires quantitative analyses of the airflow not provided by thermal sensors. Nasal air pressure, however, provides a quantitative measurement of airflow sufficiently accurate to detect both hypopneas and flow-limited breaths. In this project an untethered, miniature, self-applied ambulatory unit (AirTrac) will be built to measure airflow from nasal pressure and record data for PC download. The AirTrac will detect apneas, hypopneas and flow-limited breaths and provide basic event rates and visual data display on the PC. In phase I a prototype system was developed and found to produce results similar to that of a polysomnogram. In phase II automatic data analyses programs will be integrated into the monitor and the system tested in clinical trials. This device could facilitate clinical screening and treatment evaluations for SRBD as part of the continuum of care in sleep medicine and could also expand opportunities for clinical research.

Thesaurus Terms:
biomedical equipment development, home health care, patient monitoring device, respiratory airflow disorder, respiratory airflow measurement, sleep disorder
automated data processing, clinical trial, computer data analysis, computer human interaction, computer program /software, computer system design /evaluation, computer system hardware, electronic recording system, online computer, polysomnography, respiratory airway pressure, sleep apnea
bioengineering /biomedical engineering, clinical research, human subject

Institution:	INDIVIDUAL MONITORING SYS, INC. (IM SYS)
	1055 TAYLOR AVE, STE 300
	BALTIMORE, MD 21286
Fiscal Year:	2003
Department:
Project Start:	01-MAR-2000
Project End:	30-JUN-2005
ICD:	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
IRG:	ZRG1

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