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Abstract

Grant Number:	2R44HL068463-02A1
PI Name:	LEVENDOWSKI, DANIEL J.
PI Email:	dan@b-alert.com
PI Title:
Project Title:	Automated Detection of Sleep Disordered Breathing

Abstract: DESCRIPTION (provided by applicant): The Apnea Risk Evaluation System (ARES) is an inexpensive, in-home method assessing for sleep-disordered breathing. ARES utilizes expert software to integrate analysis of nocturnal oxygen saturation, pulse rate, snoring sounds, head position/movement recordings acquired with a self-applied, portable single-site (forehead) device with analysis of responses to a clinical questionnaire. During Phase II, an ARES reflectance sensor will be developed to optimize results obtained from in-home recordings and to reduce cost and between-unit variability. The ARES pulse oximeter will be compared to commercial oximeters and co-oximetry during normoxic and hypoxic steady state conditions and during breath-holds at functional residual capacity. Additional algorithms will be implemented to assist in the characterization of abnormal respiratory events and to identify probable arousals. To broaden clinical acceptance, the off-line analysis software will be expanded to allow researchers and sleep medicine professionals to visually inspect the automated ARES algorithm results and modify the scoring.

Thesaurus Terms:
computer assisted diagnosis, computer system design /evaluation, diagnosis design /evaluation, method development, respiratory disorder diagnosis, sleep apnea
catheterization, cost effectiveness, head movement, oximetry, oxyhemoglobin, respiratory gas analyzer
clinical research, human subject

Institution:	ADVANCED BRAIN MONITORING, INC.
	2850 PIO PICO DR, STE A
	CARLSBAD, CA 92008
Fiscal Year:	2003
Department:
Project Start:	30-SEP-2001
Project End:	30-JUN-2005
ICD:	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
IRG:	ZRG1

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