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Abstract

Grant Number:	5R44AI046913-03
PI Name:	SIMKULET, MICHELLE D.
PI Email:	simkuletm@intersci.com
PI Title:
Project Title:	360 Degree Sinuscope with Integrated Forward View

Abstract: All endoscopic applications would benefit from a significant increase in available field of view though major modification to the endoscope. Under the Phase I effort, InterScience Inc. has successfully demonstrated the application of its patented 360-degree/forward view imaging technology to small diameter digit endoscopes, with specific application to sinus surgery. In Phase II, we will significantly advance the development of this technology to the point of assembling fully integrated prototype 360 degree/forward view endoscopic systems and conducting initial clinical evaluation of the devices. The proposed Phase II effort will comprise optical design, development and assembly of a custom rigid endoscope system with an integrated 360 degree and forward view and real time image processing. Initial efforts include laboratory optical testing and cadaver testing for system optimization, and finally clinical evaluation in sinus surgery and airway evaluation applications. A successful Phase II effort will provide the necessary foundation to transfer the technology to additional endoscopic applications and to develop appropriate licensing arrangements with existing medical endoscope manufacturers. At this time, we have received an expression of interest from Karl Storz GmbH & Co., a worldwide leader in endoscope production, in the development and commercialization of this technology. PROPOSED COMMERCIAL APPLICATIONS: NOT AVAILABLE

Thesaurus Terms:
biomedical equipment development, diagnosis design /evaluation, endoscopy, image processing, otolaryngologic surgery, paranasal sinus, sinusitis
computer program /software, computer system design /evaluation, image enhancement
clinical research, human subject, patient oriented research

Institution:	INTERSCIENCE, INC.
	105 JORDAN RD
	TROY, NY 12180
Fiscal Year:	2003
Department:
Project Start:	01-JUL-2000
Project End:	30-APR-2004
ICD:	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
IRG:	ZRG1

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