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Abstract

Grant Number:	5R44CA083398-03
PI Name:	CHEE, MARK S.
PI Email:	mchee@illumina.com
PI Title:	VICE PRESIDENT, GENOMICS
Project Title:	Parallel Array Processor

Abstract: DESCRIPTION (provided by applicant): Microarrays are designed to allow many experiments to be carried out simultaneously on a single sample, and are highly efficient in this regard. However, commercially available microarray technologies are not designed for the analysis of large numbers of samples, and are costly and cumbersome to apply in this way. There is an increasing need for an array technology that will permit many samples to be processed efficiently, accurately, cost-effectively, and reproducibly. We have developed an array technology with these requirements in mind. This project aims to develop further a system for parallel processing of arrays. The system is based on a matrix of arrays in a microtiter format, and aims to provide researchers with a capability for large-scale analysis of complex genetic systems that is currently attainable only in costly large-scale production environments. It will allow researchers to carry out array-based SNP genotyping and RNA profiling experiments on thousands of samples per day. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

Thesaurus Terms:
biomedical automation, biomedical equipment development, computer system design /evaluation, high throughput technology, microarray technology, parallel processing
complementary DNA, fiber optics, fluorescent dye /probe, genotype, messenger RNA, nucleic acid purification, oligonucleotide, robotics
cell line, clinical research, nucleic acid hybridization, single nucleotide polymorphism

Institution:	ILLUMINA, INC.
	9885 TOWNE CENTRE DR
	SAN DIEGO, CA 921211975
Fiscal Year:	2003
Department:
Project Start:	23-JUL-1999
Project End:	31-MAR-2004
ICD:	NATIONAL CANCER INSTITUTE
IRG:	ZRG1

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