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Abstract

Grant Number:	5R44RR015136-03
PI Name:	ONG, KEAT G.
PI Email:	kzol@psu.edu
PI Title:
Project Title:	Magnetoelastic Sensors for Biomedical Monitoring

Abstract: DESCRIPTION (provided by applicant): This proposal seeks support for the further development of a new sensor technology that enables in-situ or in-vivo remote query real time measurement of physical and chemical parameters. In response to a magnetic field impulse the ribbon-shaped magnetoelastic sensors efficiently convert magnetic energy to elastic energy, which mechanically deforms the sensor. Since the material is magnetostrictive, the mechanical deformation acts to generate a time-varying magnetic flux that can be detected remotely with a pick-up coil. The mechanical deformation demonstrates a resonance the frequency of which is dependent upon sensor mass loading. Hence by combining a pH sensitive polymer with the magnetoelastic substrate a wireless, passive, inexpensive pH sensor is achieved. In Phase I we have demonstrated the feasibility of magnetoelastic sensors for remote query measurement of pH independently of background salt concentration, and reduced the sensor monitoring electronics to a notebook scale. The key goals of Phase II include a further extension in signal processing capability with miniaturization of the electronics package, optimization of polymer composition and response time, design and fabrication of a capsule within which the sensor is placed for introduction into the esophagus, and evaluation of sensor performance when used for in-vivo pH measurements (in pigs). PROPOSED COMMERCIAL APPLICATION: Wireless in-vivo measurement of gastric pH from passive, inexpensive disposable sensors would be a great improvement over current technology for monitoring of esophageal symptoms which require a trans-nasal catheter. The wireless, remote query nature of the sensor technology would also find great utility for in-situ monitoring of biological chemical analyte concentrations such as glucose.

Thesaurus Terms:
biomedical equipment development, elasticity, magnetic field, mechanical pressure, monitoring device, telemetry
acidity /alkalinity, consumable /disposable biomedical equipment, gastric acid, gastrointestinal function, miniature biomedical equipment, temperature
swine

Institution:	SENTECH CORPORATION
	200 INNOVATION BLVD, STE 236
	STATE COLLEGE, PA 16803
Fiscal Year:	2003
Department:
Project Start:	01-APR-2000
Project End:	31-MAR-2004
ICD:	NATIONAL CENTER FOR RESEARCH RESOURCES
IRG:	ZRG1

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