Abstract
| Grant Number: | 5R44NS045407-03 |
| Project Title: | Surgical Monitor for Detection of Spinal Cord Injury |
Abstract:
DESCRIPTION (provided by applicant): Somatosensory evoked potential (SEP) monitoring during spinal surgery has been associated with a 61% reduction in major neurological deficits. However, visual interpretation of signals is not always accurate, and a significant learning curve has been demonstrated. Therefore, we embarked on a course to develop a novel SEP monitor equipped with the latest in wireless and digital signal processing technology to continuously monitor spinal cord function. We propose the development of a toolbox of techniques which will significantly advance spinal cord assessment during surgery, including:
Integration of noise reduction via single-sweep rejection and filtering
Investigation of the coherence of individual spectral components of the SEP and
Incorporation of wireless multi-channel stimulation & monitoring
Evaluation of the resulting next-generation real-time monitor in a clinical study
It is our vision to translate these hardware and software innovations into a useful device to assist the clinician in improving the outcome of the patient undergoing spinal surgery.
Thesaurus Terms:
biomedical equipment development, evoked potential, patient monitoring device, somesthetic sensory cortex, spinal cord injury, spinal cord surgery, surgery material /equipment
computer program /software, electrophysiology, nerve decompression
bioengineering /biomedical engineering, clinical research, human subject
| Institution: | INFINITE BIOMEDICAL TECHNOLOGIES, LLC |
| 3600 CLIPPER MILL ROAD #410 |
| BALTIMORE, MD 21211 |
| Fiscal Year: | 2005 |
| Department: | |
| Project Start: | 01-APR-2003 |
| Project End: | 31-DEC-2007 |
| ICD: | NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
| IRG: | ZRG1 |
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