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Abstract

Grant Number: 7R44HL079782-03
Project Title: Small Animal Fourier Domain OCT Microscope
PI Information:NameEmailTitle
GROSHONG, BENNETT bgroshong@bioptigen.com

Abstract: DESCRIPTION (provided by applicant): This Phase II Small Business Innovation Research application will continue the development of the advanced OCT microscope system targeting applications in imaging small animals such as Drosophila, zebrafish, Xenopus, chick embryo and others. The result of the Phase I project was a working OCT microscope with excellent performance characteristics. For the Phase II project, additional functionality will be added including high throughput imaging using a motorized stage and advanced software, Doppler imaging, and integrated 3-D imaging and analysis. Engineering development will continue as the system is moved from the current beta prototype to a commercial system. The result of this Phase II project will be a commercially available OCT microscope with state of the art performance and an easy to operate user interface.. Our team of investigators, subcontractors, and consultants includes experts in optoelectronic component manufacturing (the basis of OCT technology), optical sensing, and one of the original developers of OCT systems for small animal imaging.

Thesaurus Terms:
biomedical equipment development, high throughput technology, microscopy, optical tomography
Animalia, biological model, computer program /software, computer system design /evaluation, image processing, spectrometry, three dimensional imaging /topography
bioengineering /biomedical engineering, bioimaging /biomedical imaging, handbook

Institution: BIOPTIGEN, INC.
BPX 13569
DURHAM, NC 27709
Fiscal Year: 2006
Department:
Project Start: 01-AUG-2004
Project End: 30-NOV-2008
ICD: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
IRG: ZRG1


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