Travel to Knoxville, Tennessee
Knoxville is easily reached by flights from North American cities to Knoxville McGee Tyson Airport (TYS). There are numerous connecting flights to Knoxville from Atlanta, Chicago, Cincinnati, and other international hub cities. Nashville (BNA) is an alternative (160 miles drive). The drive from Nashville is an easy drive on Interstate 40 through the countryside, giving a chance to view the magnificent colors. Another possibility is Atlanta (ATL) at 200 miles. Most of the drive is through the countryside on Interstate 75, but the first 30 miles are in metro Atlanta.
Link to Knoxville Tourism https://www.knoxville.org/.