M3A  MIC Plenary and 2015 Hoffman Award Lecture

Wednesday, Nov. 4  08:30-10:00  Golden Pacific Ballroom

Session Chair:  Adam Alessio, University of Washington, United States; Lawrence MacDonald, University of Washington, United States

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(08:30) M3A-1, Acceptance Lecture for 2015 Edward J Hoffman Medical Imaging Scientist Award

M. A. King

Radiology, University of Massachusetts, Worcester, MA, USA
NMISC awards introduction (Glenn Wells, NMISC awards sub-committee chair) Introduce Hoffman Recipient (Miles Wernick) Acceptance Lecture for 2015 Edward J Hoffman Medical Imaging Scientist Award Recipient Michael King, University of Massachusetts

(09:10) M3A-2, MULTISCALE CHALLENGES IN BRAIN SCIENCES: Bridging Gaps in Knowledge and Understanding

M. Ellisman

Neurosciences and Bioengineering, University of California San Diego, San Diego, CA, USA
A grand goal in neuroscience research is to understand how the interplay of structural, chemical and electrical signals in and between cells of nervous tissue gives rise to behavior. We are rapidly approaching this horizon as neuroscientists make use of an increasingly powerful arsenal of tools and technologies for obtaining data, from the level of molecules to nervous systems, and engage in the arduous and challenging process of adapting and assembling neuroscience data at all scales of resolution and across disciplines. This talk will highlight projects in which development and application of new contrasting methods and imaging tools have allowed us to observe otherwise hidden relationships between cellular, subcellular and molecular constituents of nervous systems. Application to neurodegenerative diseases will be described. New chemistries for carrying out correlated light and electron microscopy will be revealed, as well as recent advances in large-scale high-resolution 3D reconstruction with TEM and SEM based methods.